. 2015 Apr 7;10(4):e0121887. doi: 10.1371/journal.pone.0121887

Table 1. Differentially expressed genes encoding iron metabolism proteins regulated by serum, Epi, NE and DA.

Gene locus_tag	Name	Function	Serum		Epi		NE		DA
Gene locus_tag	Name	Function	Fold change	p-value	Fold change	p-value	Fold change	p-value	Fold change	p-value
APJL_0076	tonB2	TonB energy transducing protein	13.33	1.62E-05	0.14	3.68E-02	0.07	1.76E-02	0.06	2.36E-02
APJL_0077	exbD2	biopolymer transport protein	11.80	2.37E-04	0.10	3.41E-03	0.10	9.62E-03	0.08	1.64E-02
APJL_0078	exbB2	biopolymer transport protein	12.75	7.75E-07	0.09	3.50E-03	0.08	9.77E-03	0.07	8.86E-03
APJL_0128	yfeD	iron (chelated) transport system membrane protein	2.16	2.51E-04	0.43	3.02E-04	0.22	3.85E-03	0.20	2.72E-04
APJL_0286	frpB	iron-regulated outer membrane protein	7.88	4.39E-05	0.09	5.10E-03	0.11	2.12E-02	0.10	1.27E-02
APJL_0554	cirA	outer membrane receptor proteins, mostly Fe transport	3.42	1.68E-03	0.32	3.94E-03	0.35	7.76E-03	0.27	4.58E-03
APJL_0665	-	high-affinity Fe²⁺/Pb²⁺ permease	5.71	2.00E-02	0.13	1.74E-02	0.21	1.75E-02	0.17	1.03E-02
APJL_1065	hgbA	hemoglobin and hemoglobin haptoglobin-binding protein 4	3.22	1.42E-03	0.27	1.33E-03	0.21	1.36E-03	0.21	1.82E-03
APJL_1066	hugZ	heme iron utilization protein	44.51	1.52E-04	0.01	1.88E-02	0.02	9.44E-06	0.01	1.20E-04
APJL_1312	-	iron-regulated outer membrane protein	11.63	4.10E-04	0.08	1.96E-02	0.15	1.84E-02	0.11	1.01E-02
APJL_1597	tbpA1	transferrin-binding protein 1	4.00	1.03E-02	0.29	3.98E-02	0.23	5.24E-03	0.25	8.63E-03
APJL_1598	tbpB1	transferrin-binding protein 2	5.12	7.87E-04	0.18	3.36E-04	0.17	2.97E-03	0.20	9.98E-04
APJL_1599	exbD	biopolymer transport protein	6.26	3.84E-03	0.12	2.19E-03	0.14	1.49E-04	0.11	5.66E-04
APJL_1600	exbB	biopolymer transport protein	6.38	1.21E-04	0.16	1.59E-04	0.14	6.34E-04	0.11	1.19E-03
APJL_1601	tonB1	periplasmic protein	5.81	9.66E-04	0.18	2.00E-02	0.18	1.76E-02	0.22	4.21E-07
APJL_1922	-	outer membrane receptor proteins, mostly Fe transport	0.17	4.12E-03	2.27	1.68E-02	3.20	7.60E-03	3.68	5.09E-06
APJL_2000	-	hemoglobin receptor precursor	12.63	9.85E-06	0.12	2.19E-02	0.09	7.86E-04	0.08	2.39E-05
APJL_2060	hbpA2	heme-binding protein A	4.53	1.21E-04	0.22	1.25E-02	0.28	2.66E-04	0.23	3.04E-02
APJL_2064	fhuD	ferrichrome-binding periplasmic protein	2.74	2.61E-03	0.41	3.27E-03	0.36	2.31E-03	0.32	1.68E-03
APJL_2065	fhuB	ferrichrome uptake protein	4.30	2.76E-03	0.21	6.56E-04	0.21	8.77E-04	0.17	3.32E-03
APJL_2066	fhuA	outer membrane ferric hydroxamate receptor	3.22	2.69E-04	0.38	4.97E-02	0.26	2.66E-02	0.24	6.53E-03