Appendix Table 1.

Evidence-based Non-pharmacologic Delirium Prevention Interventions

Risk Factors	Details
Cognition / Orientation	Cognitive stimulation activities Orientation board with names of care team members and daily schedule Orienting communication
Early mobility	Ambulation or active range-of-motion exercises Minimizing use of immobilizing equipment
Hearing	Portable amplifying devices and special communication techniques, with daily reinforcement Ear wax clearing as needed
Sleep-wake cycle preservation	Warm milk or herbal tea, relaxation tapes or music, and back massage Unit-wide noise reduction strategies and schedule adjustments to allow uninterrupted sleep
Vision	Visual aids (glasses, magnifying lenses) and adaptive equipment (large illuminated telephone keypads, large print books, fluorescent tape on call bell), with daily reinforcement of their use
Hydration	Encourage fluids Feeding assistance and encouragement during meals