Table 2. Demographic, clinical, and molecular data for patients with newly diagnosed anaplastic astrocytic tumours.
Number of patients | Percentage | |
---|---|---|
Gender | ||
Male | 16 | 43 |
Female | 21 | 57 |
Age, mean (range) | 48 (20–81) | - |
Symptoms | ||
Weakness | 15 | 41 |
Sensory | 5 | 14 |
Seizure | 16 | 43 |
Headache | 10 | 27 |
Vision | 3 | 8 |
Dizziness | 3 | 8 |
Surgery | ||
Biopsy only | 12 | 32 |
Partial resection | 22 | 60 |
Gross total resection | 3 | 8 |
Adjuvant therapy | ||
Yes | 33 | 89 |
Chemotherapy | 27 | 73 |
Radiation therapy | 32 | 87 |
Chemo + radiation | 25 | 68 |
Outcome | ||
Clinical progression | 23 | 62 |
Death | 12 | 32 |
Histological subtype | ||
Anaplastic astrocytoma | 28 | 76 |
Anaplastic oligoastrocytoma | 9 | 24 |
IDH1-R132H mutation status | ||
Positive | 18 | 49 |
Negative | 19 | 51 |
1p/19q status | ||
Loss of 1p | 1 | 3 |
Loss of 19q | 2 | 5 |
Loss of 1p and 19q | 0 | 0 |