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. 2015 Apr 7;10(4):e0122591. doi: 10.1371/journal.pone.0122591

Fig 5. Effects of TNPs on mammary gland tight junction proteins ZO-1 and occludin after four doses of TNPs exposure (2, 6, 8 mg/kg) to dams at LDs 2, 4, 6 and 8.

Fig 5

(A) A plausible mechanistic schematic showing TNPs made cell shedding and loose the tight junction between the mammary gland epithelial cells through oxidative stress. (B) Western blot of ZO-1 and occludin in mammary glands. (C) Bar graphs show relative levels of tight junction proteins ZO-1 and occludin by normalizing PBS group to 1.0. The symbol * represents significant difference from the PBS group (P<0.05), (n = 3).