Skip to main content
. 2015 Apr 7;10(4):e0123293. doi: 10.1371/journal.pone.0123293

Fig 11. LPS and SR-A ligands regulate uptake, acidification and proteolysis of endocytosed antigens.

Fig 11

(A) Effects of 1-day pre-treatment with 100 ng/ml LPS on the total uptake of AF-OVA-Cl, internalisation of pHr-OVA-Cl and degradation of DQ-OVA by BM-DC and PEM. (B, C) Effects on indicated ligands on the acidification of pHr-OVA-Cl-containing endosomes (B) and proteolytic digestion of DQ-OVA (C) in BM-DC and PEM. The results shown are averages +SEM from 3 independent experiments, each performed in 4 replicates. The data were analysed by the Student’s t-test (A) or by ANOVA, with the Dunnett’s post-test applied to compare the control (“medium”) with other groups (B, C). *, p < 0.05.