Table 1. Effect of chlorogenic acid supplementation on physical characteristics and other parameters in plasma, whole blood, liver and muscle in db/db and db/m mice.* .
| Items | db/m-CON | db/m-CGA | db/db-CON | db/db-CGA | |
|---|---|---|---|---|---|
| Physical parameters | Initial body weight (g) | 16.9±0.87 a | 17.0±0.73 a | 26.6±1.05 b | 26.7±0.90 b |
| Final body weight (g) | 23.1±0.95 a | 22.3±1.16 a | 58.5±1.25 b | 58.6±1.64 b | |
| Lee’s index | 14.2±0.22 a | 13.9±0.23 b | 19.1±0.19 c | 19.0±0.23 c | |
| Visceral adipose (%) | 4.56±0.60 a | 2.66±0.76 b | 12.7±0.34 c | 11.5±1.02 d | |
| Plasma | FPG (mmol/L) | 7.02±0.89 a | 5.52±2.10 a | 20.5±3.96 b | 14.6±4.04 c |
| FFA (mmol/L) | 0.88±0.09 a | 0.63±0.18 b | 1.42±0.36 c | 1.35±0.17 c | |
| TG (mmol/L) | 1.44±0.26 a | 1.29±0.20 a | 1.53±0.14 a | 1.43±0.23 a | |
| TC (mmol/L) | 2.76±0.28 a | 2.76±0.26 a | 5.21±0.35 b | 4.83±0.45 b | |
| Insulin (mIU/L) | 9.18±1.02 a | 20.47±3.51 b | 10.24±1.48 a | 13.26±2.08 a | |
| Whole blood | HbA1c (%) | 15.7±4.74 a | 8.62±2.44 b | 35.8±6.27 c | 27.6±5.86 d |
| Liver | TG (mg/g) | 8.96±1.77 a | 8.78±1.52 a | 21.4±3.39 b | 53.9±10.92 c |
| Glycogen (mg/g) | 5.63±1.77 a | 5.63±1.77 a | 10.8±2.44 b | 8.53±1.29 c | |
| Muscle | TG (mg/g) | 3.52±0.41 a | 3.07±0.34 a | 14.3±2.07 b | 14.6±1.42 b |
| Glycogen (mg/g) | 1.21±0.30 a | 1.19±0.29 a | 1.00±0.16 a | 1.01±0.17 a |
a,b,c,d Those means not sharing a common letter in the same row are significantly different between groups (n = 8) (P <0.05).
*The values are expressed as the means±SD.