Table 1.

Benefits of research registration.

Stakeholder	Benefit
Research and clinical community	❖ Reduce publication and reporting bias (not all studies performed are published – especially negative studies) ❖ Increase transparency ❖ Identify on-going studies in their field – the cutting edge and gaps ❖ Aids research quality – allows for open and early peer-review of study objectives and methods and their refinement ❖ Aids guideline development and evidence synthesis/systematic review ❖ global collaboration between researchers – more multicentre studies
Editors and peer-reviewers	❖ Compare study findings with registered study protocol ❖ Evidence-based medicine
Commissioners, funders and wider society	❖ Reduce unnecessary duplication saving funds
Institutions	❖ Increased collaboration – research that's more global, multicentre and more interdisciplinary
Patients and the public	❖ Can find out about research of interest to them (e.g. HIV treatments) ❖ Respect, dignity and ethics – people who enter studies expect a permanent record of it.