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Antidepressant use in the first 3 months (0–3 months) and second 3 months (3–6 months) of treatment by pain cohort. Clinically significant pain was defined as overall pain VAS greater than 30 mm at baseline. SNRI serotonin noradrenaline reuptake inhibitor, SSRI selective serotonin reuptake inhibitor, TCA tricyclic antidepressant, VAS visual analog scale
