Table 3.
Economic input and associated costs (in 2008 Canadian dollars)
| Variable | Distribution | Low | High | Value | Source |
|---|---|---|---|---|---|
| Direct costs | |||||
| Clinician/hospital charges | |||||
| Pharmacist dispensing fee | Uniform | $6.00 | $15.00 | $10.50 | MOHLTC: dispensing fees [40] |
| Initial assessment family practice | Uniform | $42.53 | $78.98 | $60.75 | MOHLTC: schedule of benefits [41] |
| Follow-up family practice | Uniform | $21.25 | $39.46 | $30.35 | MOHLTC: schedule of benefits [41] |
| Initial assessment psychiatry | Uniform | $113.74 | $211.22 | $162.48 | MOHLTC: schedule of benefits [41] |
| Follow-up psychiatry | Uniform | $57.72 | $107.19 | $82.45 | MOHLTC: schedule of benefits [41] |
| Hospitalization cost (10-day period) | Uniform | $3,416.00 | $6,340.00 | $4,878.00 | Health Canada [42]; CIHI [43] |
| Pharmacotherapy (mean daily cost) | |||||
| Initial 1st line | Uniform | $0.70 | $1.30 | $1.00 | MOHLTC:ODB: formulary [44] |
| Initial benzodiazepine adjunctive 1st line | Uniform | $0.80 | $1.49 | $1.15 | MOHLTC:ODB: formulary [44] |
| Initial benzodiazepine monotherapy | Uniform | $0.10 | $0.19 | $0.15 | MOHLTC:ODB: formulary [44] |
| Initial 3rd line | Uniform | $0.83 | $1.55 | $1.19 | MOHLTC:ODB: formulary [44] |
| Maintenance 1st line | Uniform | $0.96 | $1.78 | $1.37 | MOHLTC:ODB: formulary [44] |
| Maintenance benzodiazepine adjunctive 1st line | Uniform | $1.12 | $2.07 | $1.59 | MOHLTC:ODB: formulary [44] |
| Maintenance benzodiazepine monotherapy | Uniform | $0.16 | $0.30 | $0.23 | MOHLTC:ODB: formulary [44] |
| Maintenance 3rd line | Uniform | $2.04 | $3.79 | $2.91 | MOHLTC:ODB: formulary [44] |
| Titrated 1st line | Uniform | $1.19 | $2.20 | $1.70 | MOHLTC:ODB: formulary [44] |
| Titrated benzodiazepine adjunctive 1st line | Uniform | $1.41 | $2.63 | $2.02 | MOHLTC:ODB: formulary [44] |
| Titrated benzodiazepine monotherapy | Uniform | $0.16 | $0.29 | $0.22 | MOHLTC:ODB: formulary [44] |
| Titrated 3rd line | Uniform | $4.04 | $7.50 | $5.77 | MOHLTC:ODB: formulary [44] |
| Indirect costs | |||||
| Absenteeism 6 months (2 days/month) | Uniform | $1,465.12 | $2,719.60 | $2,092.72 | Kessler [45]; Statistics Canada [46] |
| Resource use | |||||
| Treatment seeking rate | Triangular | 0.1000 | 0.3300 | 0.2600 | Wang [47] |
| Hospitalization rate | Triangular | 0.0000 | 0.1200 | 0.0600 | CIHI [43] |
| Discount rate | Uniform | 0.0000 | 0.0500 | 0.0500 | |
CIHI Canadian Institutes of Health Information, MOHLTC Ministry of Health and Long Term Care, ODB Ontario Drug Benefit