Table 1. Chemopreventive effect of quercetin on DMBA croton oil induced skin carcinogenesis in mice.
| Treatment | Body weight (g) | No. of papilloma | Tumor size (mm) | Average latent perioda | |
|---|---|---|---|---|---|
| Initial | Final | ||||
| Group I (normal) | 38.12±4.23 | 37.56±5.43 | |||
| Group II (control) | 26.26±2.16 | 22.75±11.24 | 10.16±5.03 | 2.06±0.37 | 10.10±5.17 |
| Group III (treated) | 29.57±1.18 | 26.15±12.88 | 1.50±1.04 | 0.93±0.24 | 13.10±0.76 |
| Group IV (treated) | 29.64±1.50 | 27.04±13.25 | 1.16±0.75 | 0.87±0.22 | 13.59±0.68 |
a
The lag between the application of the promoting agent and the appearance of 50% of tumors were determined. Average latent period = Σfx/n, f is the number of tumors appearing each week; x is the number of weeks and n is the total number of tumors.