Fig. 1.
Experimental schedule for the effects of UE2316 treatment on spatial and contextual fear memory in a vehicle controlled cross over design. Prior to behavioural testing (Y-maze (2 h inter-trial interval (ITI)) and fear conditioning (FC)), 24 m aged mice were treated via subcutaneously implanted Alzet osmotic minipumps with UE2316 (10 mg/kg/day) or vehicle (n = 8–9/group).