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. 2015 Mar 25;12:23. doi: 10.1186/s12950-015-0068-1

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© Shi et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effect of chronic intermittent hypobaric hypoxia (CIHH) pretreatment on pathologic morphology of synovial tissue in collagen-induced arthritis rat. A: Control rats displayed normal synovial tissue; B: Collageniinduced arthritis (CIA) rats displayed obvious hyperplasia with inflammatory infiltration in liner and underlayer of liner; C: CIHH treated CIA (CIHH+CIA) rats did not displayed significant difference from control rats. (H-E staining × 100).