Table 2.
Echocardiographic functional parameters for female and male rats post-MI
| Female | Male | |||||||
|---|---|---|---|---|---|---|---|---|
| Week 1 | Week 1 | Week 6 | Week 6 | Week 1 | Week 1 | Week 6 | Week 6 | |
| Sham | MI | Sham | MI | Sham | MI | Sham | MI | |
| FAC (%) | 63±4 | 34±6* | 67±3 | 29±7* | 66±7 | 32±4* | 63±4 | 31±7* |
| E (cm/s) | 69±2 | 70±2 | 73±6 | 85±2* | 59±2 | 73±1 | 67±4 | 87±2* |
| A (cm/s) | 24±1 | 20±1 | 29±5 | 20±1 | 30±5 | 28±1 | 30±6 | 28±2 |
| E/A ratio | 3±1 | 5±3 | 3±1 | 6±4* | 1±0.5 | 3±2 | 2±0.2 | 5±3* |
FAC=fractional area change; E=E wave; A=A wave; Data are shown as means±SD. Two-way ANOVA and Bonferroni tests were applied for comparisons.
*
P<0.05 vs. Sham on first and sixth week