Table 2. Mean difference in adiposity (l) and IHCL (ratio CH2:H2O) at follow-up, boys compared with girls (adjusted for weight at imaging).
Baseline |
Follow-up |
|||||
---|---|---|---|---|---|---|
R2 | Adjusted mean difference | P | R2 | Adjusted mean difference | P | |
n | 69 | 69 | ||||
Total AT | 0.58 | −0.075 (−0.154, 0.001) | 0.05 | 0.63 | −0.193 (−0.312, −0.074) | 0.002 |
Superficial subcutaneous abdominal AT | 0.48 | −0.018 (−0.033, −0.002) | 0.02 | 0.44 | −0.039 (−0.070, −0.007) | 0.02 |
Superficial subcutaneous non-abdominal AT | 0.59 | −0.046 (−0.100, 0.008) | 0.09 | 0.64 | −0.124 (−0.205, −0.043) | 0.003 |
Deep subcutaneous abdominal AT | 0.43 | −0.002 (−0.004, 0.001) | 0.23 | 0.25 | −0.007 (−0.014, −0.001) | 0.04 |
Deep subcutaneous non-abdominal AT | 0.23 | −0.002 (−0.003, 0.000) | 0.10 | *0.22 | −9.6%*(−26.1%, 10.6%) | 0.32** |
Internal abdominal AT | 0.10 | −0.001 (0.004, 0.003) | 0.77 | 0.01 | −0.001 (−0.009, 0.006) | 0.69 |
Internal non-abdominal AT | 0.33 | −0.007 (−0.015, 0.001) | 0.07 | 0.40 | −0.019 (−0.032, −0.005) | 0.007 |
Ratio (IA/SCA)0.6 | 0.02 | 0.01 (−0.01, 0.02) | 0.37 | 0.07 | 0.01 (−0.01, 0.02) | 0.38 |
n | 54 | 54 | ||||
IHCL | 0.02* | −6.4% (−39.7%, 45.2%)* | 0.76** | 0.04* | −31.3% (−60.7%, 20.1%)* | 0.18** |
Abbreviations: AT, adipose tissue; IA, internal abdominal; IHCL, intrahepatocellular lipid; SCA, subcutaneous abdominal.
P represents significance of infant sex in overall analyses. Data are mean and (95% confidence intervals) and P-values from multivariable regression, except where * denotes percentage difference (95% confidence intervals) following log transformation and ** denotes P-values from multivariable regression of natural log-transformed data (performed using transformed data due to non-normal distribution of residuals).