Fig. 4.
Predicted AUC ratios of victim drugs in the presence of various inhibitors. AUC area under the plasma concentration-time curve, SIL sildenafil, SIR sirolimus, TIC ticagrelor, TAC tacrolimus, DRO dronedarone, POS posaconazole, BOC boceprevir, SAQ saquinavir, TEL telaprevir, KET ketoconazole