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. 2014 Oct 2;16(6):1321–1333. doi: 10.1208/s12248-014-9664-x

Fig. 7.

Fig. 7

Visual predictive check (VPC) plots of the integrated PK model for arctigenin (AR) and its metabolites (AG and AA) after intravenous (IV) or oral administration. The gray-shaded areas represent the 95% confidence intervals of the corresponding 2.5th, 50th, and 97.5th percentiles of the simulated data; the red-dashed areas represent the 2.5th and 97.5th percentiles of the observed data; and red solid line represents median of the observed data