A summary of the maximal initial changes in (HR), mean arterial blood pressure (MAP), and hindquarter (HQR), renal (RR) and mesenteric (MR) vascular resistances produced by three injections of hypertonic saline (750–3000 µmol/kg, i.v.) in pentobarbital-anesthetized rat (n=5) subjected to hemorrhage (5.9 ± 0.5 ml/rat at 1.5 ml/min). The values are expressed as the mean ± SEM of the percent changes form pre-injection baseline values. *P < 0.05, significant response.