Table 3.

Effects of hypertonic saline on hemodynamic parameters in hemorrhaged rats

		Post-saline values
Parameter	post-HEM, 0 min pre-sal1	post-sal1 pre-sal2	post-sal2 pre-sal3	post-sal3
ΔHR (%)	−18 ± 4*	−17 ± 2*	−15 ± 3*	−9 ± 6†
ΔMAP (%)	−68 ± 3*	−54 ± 3*,†	−31 ± 7*,†	+2 ± 3†
ΔHQR (%)	−23 ± 7*	−30 ± 7*	−9 ± 6†	−3 ± 4†
ΔRR (%)	0 ± 10	−9 ± 6	−19 ± 7*	+13 ± 5*
ΔMR (%)	−11 ± 11	−3 ± 8	+29 ± 10*,†	+57 ± 6*,†

The data are shown as mean ± SEM of the percent changes from pre-hemorrhage (HEM) values. The column designated as post-HEM/pre-sal1 shows the hemodynamic changes in response to HEM. The columns designated post-sal1/pre-sal2, post-sal2/pre-sal3 and post-sal3,summarize the hemodynamic status after the first, second and third injections of hypertonic saline, respectively.

HR = heart rate. MAP = mean arterial blood pressure. HQR = hindquarter vascular resistance. RR = renal vascular resistance. MR = mesenteric vascular resistance.

^*P < 0.05, significant change from pre-HEM values.

^†P < 0.05, pre-sal2, pre-sal3,orpost-sal3 versus pre-sal1.