Table 1.
Silica NPs alter GSH concentration of PBMCs
Cellular treatment and condition | Mean ± SEM (N)* |
---|---|
Untreated control cells showing no stress | 24 ± 0.9 (351) |
Cells exposed to 100-nm particles and showing no stress | 60 ± 2.8 (130) |
Cells exposed to 100-nm particles and showing stress | 5 ± 1.2 (48) |
Cells exposed to 10-nm particles and showing no stress | 76 ± 3.8 (264) |
Cells exposed to 10-nm particles and showing stress | 13 ± 2.0 (28) |
*GSH concentration is presented as the mean number of gold particles, indicating GSH, per square micron ± S.E.M. N is the total number of 0.5 micron squared areas where gold particles were counted in each group. Each group was compared with each other using the Student’s t test and was found to be significantly different from each other using the P-level of 0.005.