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. 2015 Mar 24;15:147. doi: 10.1186/s12879-015-0906-z

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© Mossallam et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Scanning electron micrographs of adult S. mansoni female worms recovered from unimmunized group (A) and from FSm14/29-immunized group (B-F). (A) The dorsolateral surface of a female recovered from the unimmunized control group showing fine circular ridges interspaced with regular clefts and carrying conspicuous sensory bulbs (Sb), X3,500. (B) The anterior end of a female worm recovered from FSm14/29-immunized animals exhibiting extensive swelling of the forebody tegument, with evident strangulation (thick arrow), associated with small sized blebbings (Bl) in the lips of their suckers. Spines lining the edematous suckers were short, irregularly positioned and chubby in appearance (thin arrow), X500. (C) A convoluted female expressing irregularly positioned constrictions in various areas of its body (arrows), besides loss of the mid-body circular ridges with complete destruction of the external surface of the forebody, X750. (D) Kinky female surface swellings alternating with dimples (Dp), furrows (Fr), gappings (Ga), and wrinkling (Wr), X750. (E) Higher magnification verifying that the linear transverse tegumental ridges encircling the body worm were replaced by swelling induced loosing of the clefts, and fusions of ridges. This resulted in the formation of long irregular and disorganized splits, X3,500. (F) Host leucocytes attached to the tegument of the female surfaces (arrows), X7,500.