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. 2015 Mar 19;48(1):18. doi: 10.1186/s40659-015-0006-y

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© Pan et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Down-regulation of USP39 inhibits cell proliferation and colony formation ability of SMMC-7721 cells. (A) The growth curves of Con, Lv-shCon and Lv-shUSP39 infected SMMC-7721 cells. **, P < 0.01. (B) Representative images of colony formation assays of Con, Lv-shCon and Lv-shUSP39 infected SMMC-7721 cells. From top to bottom: crystals violet staining, bright field and GFP of single colony, and crystals violet staining of six-well plate. Scale bar, 25 μm. (C) Colony numbers of Con, Lv-shCon and Lv-shUSP39 infected SMMC-7721 cells. ***, P < 0.001.