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. 2015 Apr 8;10(4):e0124314. doi: 10.1371/journal.pone.0124314

Table 1. Baseline Clinical and Procedural Characteristics and Medications.

SES stratum BMS stratum
(N = 5078) (N = 5392)
Clinical Characteristics
Age, years 68.4±10.4 67.9±11.8
Age > = 75 years 1547 (31%) 1717 (32%)
Male 3624 (71%) 3922 (73%)
BMI 23.8±3.4 23.7±3.5
BMI <25.0 3408 (67%) 3745 (69%)
Hypertension 4212 (83%) 4364 (81%)
Diabetes mellitus 2069 (41%) 1787 (33%)
Diabetes with insulin therapy 520 (10%) 255 (4.7%)
Current smoking 1372 (27%) 1988 (37%)
Acute myocardial infarction 820 (16%) 2890 (54%)
Heart failure 875 (17%) 1182 (22%)
Shock at presentation 114 (2.2%) 499 (9.3%)
Multivessel disease 2966 (58%) 2420 (45%)
Mitral regurgitation grade 3/4 164 (3.2%) 230 (4.3%)
LVEF, % 59.9±12.9 57.8±13.1
Previous myocardial infarction 685 (14%) 382 (7.1%)
Previous stroke 579 (11%) 506 (9.4%)
Peripheral vascular disease 403 (7.9%) 394 (7.3%)
eGFR <30 ml/min/1.73m2, not on dialysis 198 (3.9%) 234 (4.3%)
Dialysis 228 (4.5%) 116 (2.2%)
Atrial Fibrillation 404 (8.0%) 489 (9.1%)
Anemia (Hemoglobin <11 g/dl) 582 (12%) 614 (11%)
Thrombocytopenia (Platelet <100 109/L) 72 (1.4%) 79 (1.5%)
COPD 172 (3.4%) 211 (3.9%)
Liver cirrhosis 116 (2.3%) 154 (2.9%)
Malignancy 441 (8.7%) 539 (10%)
Procedural Characteristics
Number of target lesions 1.47±0.74 1.30±0.62
Target of proximal LAD 3159 (62%) 2804 (52%)
Target of unprotected LMCA 172 (3.4%) 154 (2.9%)
Target of CTO 673 (13%) 339 (6.3%)
Target of bifurcation, 1981 (39%) 1217 (23%)
Bifurcation with side-branch stenting, 246 (4.8%) 127 (2.4%)
Total number of stents 1.90±1.22 1.46±0.82
Total stent length, mm 42.3±30.2 29.1±18.8
Total stent length >28mm 2674 (53%) 1804 (34%)
Minimum stent size, mm 2.83±0.37 3.09±0.49
Minimum stent size <3.0mm 2538 (50%) 1576 (29%)
Baseline medication
Antiplatelet therapy
Thienopyridine 5062 (99.7%) 5288 (98%)
Ticlopidine 4503 (89%) 4887 (91%)
Clopidogrel 551 (11%) 380 (7.0%)
Aspirin 5010 (99%) 5318 (99%)
Cilostazole 791 (16%) 1204 (22%)
Other medications
Statins 2737 (54%) 2594 (48%)
Beta-blockers 1418 (28%) 1717 (32%)
ACE-I/ARB 2797 (55%) 3259 (60%)
Nitrates 1882 (37%) 1789 (33%)
Calcium channel blockers 2369 (47%) 1858 (35%)
Nicorandil 1087 (21%) 1350 (25%)
Warfarin 413 (8.1%) 404 (7.5%)
Proton pump inhibitors 1183 (23%) 1498 (28%)
H2-blockers 1198 (24%) 1515 (28%)

ACE-I = angiotensin converting enzyme inhibitors, ARB = angiotensin II receptor blockers, BMI = body mass index, BMS = bare-metal stents, COPD = chronic obstructive pulmonary disease, CTO = chronic total occlusion, eGFR = estimated glomerular filtration rate, LAD = left anterior descending coronary artery, LMCA = left main coronary artery, LVEF = left ventricular ejection fraction, and SES = sirolimus-eluting stents.