Table 4. Unadjusted and Adjusted Risk of No-APT and SAPT Relative to DAPT for Serious Adverse Events beyond 1-month after index PCI.
| Unadjusted OR | (95%CI) | P value | Adjusted OR | (95%CI) | P Value | ||
|---|---|---|---|---|---|---|---|
| (A) Definite ST | |||||||
| SES stratum | SAPT | 1.92 | (1.07–3.45) | 0.03 | 2.01 | (1.12–3.61) | 0.02 |
| No-APT | 8.07 | (3.64–16.72) | <0.001 | 9.54 | (4.46–20.41) | <0.001 | |
| BMS stratum | SAPT | 0.92 | (0.47–1.91) | 0.82 | 0.89 | (0.45–1.80) | 0.75 |
| No-APT | 4.68 | (1.91–11.05) | 0.001 | 4.57 | (1.91–10.93) | 0.001 | |
| (B) Spontaneous MI | |||||||
| SES stratum | SAPT | 0.62 | (0.35–1.07) | 0.09 | 0.64 | (0.37–1.13) | 0.12 |
| No-APT | 3.86 | (1.84–7.36) | <0.001 | 3.65 | (1.82–7.30) | <0.001 | |
| BMS stratum | SAPT | 0.98 | (0.65–1.53) | 0.94 | 1.10 | (0.72–1.69) | 0.67 |
| No-APT | 2.23 | (1.07–4.30) | 0.03 | 2.29 | (1.15–4.58) | 0.02 | |
| (C) Stroke | |||||||
| SES stratum | SAPT | 0.70 | (0.53–0.91) | 0.007 | 0.75 | (0.57–0.99) | 0.04 |
| No-APT | 2.21 | (1.39–3.33) | 0.001 | 2.10 | (1.36–3.25) | 0.001 | |
| BMS stratum | SAPT | 1.05 | (0.78–1.44) | 0.74 | 1.19 | (0.88–1.62) | 0.27 |
| No-APT | 2.00 | (1.15–3.31) | 0.02 | 1.91 | (1.12–3.24) | 0.02 | |
APT = no antiplatelet therapy, BMS = bare-metal stents, CI = confidence interval, DAPT = dual-APT, OR = odds ratio, SAPT = single-APT, and SES = sirolimus-eluting stents.