Table 3.
List of experimentally validated miRNA—gene interactions for Notch signalling pathway. Interactions with Wnt and TGF-β signalling are also indicated (genes among those in Notch pathway).
| miRNA | Gene (Notch pathway) | Wnt signalling | TGF-β signalling |
|---|---|---|---|
| hsa-miR-335-5p | NUMB, MFNG, LFNG, DLL1, NOTCH3, DTX1, MAML2, JAG2 | — | — |
| hsa-miR-34a-5p | HDAC1, NOTCH2, NOTCH1, DLL1, JAG1 | — | — |
| hsa-miR-1 | CTBP1, CTBP2, NOTCH2, HDAC2, DTX1 | CTBP1, CTBP2 | — |
| hsa-miR-124-3p | RBPJ, DVL2, MAML1, JAG2 | DVL2 | — |
| hsa-miR-26b-5p | DVL3, KAT2B, EP300 | EP300, DVL3 | EP300 |
| hsa-miR-155-5p | NOTCH2, PSEN1, RBPJ | — | — |
| hsa-miR-375 | NUMB, JAG1, RBPJ | — | — |
| hsa-miR-21-5p | JAG1, NCSTN, DTX3L | — | — |
| hsa-miR-98 | DTX4, JAG1 | — | — |
| hsa-miR-122-5p | NUMBL, ADAM17 | — | — |
| hsa-miR-200c-3p | JAG1, EP300 | EP300 | EP300 |
| hsa-miR-9-5p | NCOR2, EP300 | EP300 | EP300 |
| hsa-miR-324-3p | CREBBP, DVL2 | CREBBP, DVL2 | CREBBP |
| hsa-miR-24-3p | HDAC1, NOTCH1 | — | — |
| hsa-miR-194-5p | EP300 | EP300 | EP300 |
| hsa-miR-92a-3p | KAT2B | — | — |
| hsa-miR-16-5p | NOTCH2 | — | — |
| hsa-miR-93-5p | KAT2B | — | — |
| hsa-miR-19a-3p | KAT2B | — | — |
| hsa-miR-103a-3p | NUMB | — | — |
| hsa-miR-132-3p | LFNG | — | — |
| hsa-miR-30a-5p | NOTCH1 | — | — |
| hsa-miR-200b-3p | EP300 | EP300 | EP300 |
| hsa-miR-19b-3p | KAT2B | — | — |
| hsa-miR-145-5p | APH1A | — | — |
| hsa-miR-31-5p | NUMB | — | — |
| hsa-miR-429 | EP300 | EP300 | EP300 |
| hsa-miR-10a-5p | NCOR2 | — | — |
| hsa-miR-182-5p | EP300 | EP300 | EP300 |
| Hsa-miR-374a-5p | EP300 | EP300 | EP300 |