Table 2. Correlations between principal component (PC) scores and baseline microbiological, immunological and clinical variables.
| PC1 | PC2 | |||
|---|---|---|---|---|
| Variable | Pearson’s-r | p-value | Pearson’s-r | p-value |
| Baseline CD4 cell count (x106/ml) | 0.26 | 0.02 | 0.34 | 0.001 |
| CSF lymphocyte count (x106/L) | 0.40 | <0.001 | 0.57 | <0.001 |
| CSF Neopterin (log10pg/ml) | 0.55 | <0.001 | 0.30 | 0.004 |
| CSF sCD14 (log10pg/ml) | 0.52 | <0.001 | 0.26 | 0.01 |
| CSF arginase (units) | 0.02 | 0.9 | ||
| Baseline fungal burden (CFU/ml CSF) | -0.23 | 0.03 | -0.51 | <0.001 |
| Early fungicidal activity (log10CFU/ml/day)* | -0.28 | 0.03 | -0.21 | 0.04 |
*The association between PC1 score and EFA remained significant in a linear regression model adjusted for treatment group (p = 0.03). Unadjusted p-value = 0.01.