Table 2. Pair-wise correlations (confidence intervals are provided in S2 Table) for each trait in each of the four comparison groups (MZ twin pairs living together, MZ twin pairs living apart, twin-spouse pairs, unrelated individuals) ordered by concordance in twins living together.
Twin-Twin Living Together | Twin-Twn Living Apart | Twin-Spouse | Unrelated | ||||||
---|---|---|---|---|---|---|---|---|---|
Variable | Description | Correlation | P-Value | Correlation | P-Value | Correlation | P-Value | Correlation | P-Value |
telomerelength | Telomere length | 0.9133 | 0.0000* | 0.8561 | 0.0000* | -0.0279 | 0.8270 | 0.0003 | 0.9963 |
cotinine | Cotinine | 0.9001 | 0.0000* | 0.3469 | 0.0000* | 0.2950 | 0.0189 | 0.0739 | 0.2897 |
height | Height (cm) | 0.8841 | 0.0000* | 0.9126 | 0.0000* | 0.1451 | 0.2526 | 0.0440 | 0.5265 |
triglycerides | Triglycerides (mmol/L) | 0.8838 | 0.0000* | 0.3777 | 0.0000* | 0.0783 | 0.5454 | -0.0491 | 0.4885 |
hip | Hip circumference (cm) | 0.8035 | 0.0000* | 0.6716 | 0.0000* | 0.3027 | 0.0159 | -0.0613 | 0.3812 |
BMI | Body mass index (kg/m2) | 0.8007 | 0.0000* | 0.6239 | 0.0000* | 0.2560 | 0.0464 | -0.0252 | 0.7193 |
weight | Weight (kg) | 0.7901 | 0.0000* | 0.6832 | 0.0000* | 0.2053 | 0.1125 | -0.0968 | 0.1661 |
IL6R | Interleukin-6 receptor | 0.7794 | 0.0000* | 0.8038 | 0.0000* | 0.2900 | 0.0259 | -0.1104 | 0.1189 |
waist | Waist circumference (cm) | 0.7671 | 0.0000* | 0.5477 | 0.0000* | 0.1174 | 0.3595 | -0.0626 | 0.3705 |
PCT | Platelet Cout | 0.7504 | 0.0000* | 0.6870 | 0.0000* | 0.1156 | 0.3628 | -0.0487 | 0.4870 |
MCV | Mean corpuscular volume (fl) | 0.7396 | 0.0000* | 0.7561 | 0.0000* | 0.0733 | 0.5646 | 0.1344 | 0.0542 |
basophils | Basophils (10*9/L) | 0.7245 | 0.0000* | 0.6079 | 0.0000* | 0.0254 | 0.8423 | 0.0044 | 0.9500 |
LDL | LDL cholesterol (mmol/L) | 0.7096 | 0.0000* | 0.7039 | 0.0000* | 0.0651 | 0.6093 | -0.0026 | 0.9699 |
MPV | Mean platelet volume (fl) | 0.6957 | 0.0000* | 0.7703 | 0.0000* | -0.0880 | 0.4893 | -0.0399 | 0.5691 |
RDWSD | Red cell distribution width, standard variation | 0.6936 | 0.0000* | 0.6657 | 0.0000* | 0.0309 | 0.8086 | 0.0558 | 0.4257 |
PDW | Platelet distribution width | 0.6918 | 0.0000* | 0.7456 | 0.0000* | -0.0893 | 0.4828 | -0.0138 | 0.8437 |
PLT | Platelets (10*9/L) | 0.6847 | 0.0000* | 0.6708 | 0.0000* | 0.1011 | 0.4265 | -0.0413 | 0.5556 |
cholesterol | Total cholesterol (mmol/L) | 0.6684 | 0.0000* | 0.6464 | 0.0000* | -0.0132 | 0.9176 | 0.0593 | 0.3961 |
MCH | Mean corpuscular hemoglobin (fmol) | 0.6662 | 0.0000* | 0.7019 | 0.0000* | 0.0012 | 0.9925 | -0.0252 | 0.7189 |
creatinine | Creatinine (mol/L) | 0.6657 | 0.0000* | 0.6441 | 0.0000* | 0.3282 | 0.0081 | 0.0972 | 0.1635 |
HR | Heart rate (bpm) | 0.6395 | 0.0000* | 0.3131 | 0.0001* | 0.0378 | 0.7686 | 0.0119 | 0.8643 |
DBP | Diastolic blood pressure (mmHg) | 0.6323 | 0.0000* | 0.5213 | 0.0000* | 0.0518 | 0.6868 | -0.0558 | 0.4214 |
eosinophils | Eosinophils (10*9/L) | 0.6233 | 0.0000* | 0.4949 | 0.0000* | 0.0134 | 0.9163 | -0.0014 | 0.9838 |
WHR | Waist to hip ratio (cm/cm) | 0.6026 | 0.0000* | 0.4095 | 0.0000* | -0.1052 | 0.4121 | -0.0575 | 0.4118 |
WBC | White blood cell count (10*9/L) | 0.6001 | 0.0000* | 0.5301 | 0.0000* | 0.2986 | 0.0165 | -0.0797 | 0.2634 |
lymphocytes | Lymphocytes (10*9/L) | 0.5975 | 0.0000* | 0.5353 | 0.0000* | 0.2148 | 0.0909 | -0.0489 | 0.4875 |
SBP | Systolic blood pressure (mmHg) | 0.5948 | 0.0000* | 0.5810 | 0.0000* | 0.2139 | 0.0923 | -0.0775 | 0.2636 |
insulin | Insulin (microIU/ml) | 0.5925 | 0.0000* | 0.3254 | 0.0001* | 0.1678 | 0.2041 | -0.0608 | 0.3940 |
fibrinogen | Fibrinogen (g/L) | 0.5886 | 0.0000* | 0.4423 | 0.0000* | -0.0080 | 0.9522 | -0.0248 | 0.7350 |
monocytes | Monocytes (10*9/L) | 0.5873 | 0.0000* | 0.6474 | 0.0000* | 0.0928 | 0.4693 | 0.1068 | 0.1314 |
neutrophils | Neutrophils (10*9/L) | 0.5800 | 0.0000* | 0.3687 | 0.0000* | 0.2512 | 0.0453 | -0.0529 | 0.4556 |
CRP | C-reactive protein (mg/L) | 0.5730 | 0.0000* | 0.3200 | 0.0002* | -0.1983 | 0.1287 | 0.0936 | 0.2012 |
RDWCV | Red cell distribution width, coefficient variation | 0.5708 | 0.0000* | 0.5665 | 0.0000* | -0.0895 | 0.4821 | 0.0752 | 0.2826 |
HDL | HDL cholesterol (mmol/L) | 0.5697 | 0.0000* | 0.7372 | 0.0000* | 0.0498 | 0.6960 | -0.0147 | 0.8331 |
GGT | Gamma glutamyl transpeptidase (U/L) | 0.5630 | 0.0000* | 0.5487 | 0.0000* | -0.0277 | 0.8277 | 0.0488 | 0.4853 |
MCHC | Mean corpuscular hemoglobin concentration (mmol/L) | 0.5510 | 0.0000* | 0.5076 | 0.0000* | -0.0445 | 0.7289 | 0.0966 | 0.1670 |
RBC | Red blood cell count (10*12/L) | 0.5446 | 0.0000* | 0.6880 | 0.0000* | 0.2382 | 0.0580 | 0.0722 | 0.3035 |
glucose | Glucose (mmol/L) | 0.5342 | 0.0000* | 0.4509 | 0.0000* | 0.2283 | 0.0794 | -0.1023 | 0.1496 |
HGB | Hemoglobin (mmol/L) | 0.5285 | 0.0000* | 0.4730 | 0.0000* | 0.1138 | 0.3708 | 0.0395 | 0.5735 |
HCT | Hematocrit (ratio) | 0.4834 | 0.0002* | 0.5137 | 0.0000* | 0.0950 | 0.4553 | 0.0799 | 0.2548 |
ALT | Alanine transaminase (U/L) | 0.4445 | 0.0006* | 0.3756 | 0.0000* | 0.2899 | 0.0201 | 0.0149 | 0.8313 |
AST | Aspartate aminotransferase (U/L) | 0.3495 | 0.0077 | 0.3411 | 0.0000* | 0.1013 | 0.4297 | 0.0137 | 0.8452 |
IFNg | Interferon gamma (pg/ml) | 0.3270 | 0.0205 | 0.2404 | 0.0051 | 0.1498 | 0.2704 | -0.0675 | 0.3611 |
IL8 | Interleukin-8 (pg/ml) | 0.3237 | 0.0193 | 0.4329 | 0.0000* | 0.4530 | 0.0005* | -0.0256 | 0.7236 |
GMCSF | Granulocyte-macrophage colony-stimulating factor (pg/ml) | 0.2370 | 0.0940 | -0.0499 | 0.5600 | -0.0292 | 0.8294 | 0.1685 | 0.0202 |
IL2 | Interleukin-2 (pg/ml) | 0.1461 | 0.2967 | 0.0960 | 0.2662 | -0.1095 | 0.4263 | 0.1014 | 0.1651 |
IL6 | Interleukin-6 (pg/ml) | 0.1244 | 0.3846 | 0.0931 | 0.2703 | -0.0508 | 0.7024 | -0.0115 | 0.8736 |
TNFA | Tumor necrosis factor alpha (pg/ml) | 0.0628 | 0.6651 | 0.1573 | 0.0655 | 0.1206 | 0.3851 | 0.0296 | 0.6872 |
IL1b | Interleukin-1 beta (pg/ml) | -0.0058 | 0.9682 | 0.1149 | 0.1894 | 0.1727 | 0.2117 | -0.1439 | 0.0540 |
IL10 | Interleukin-10 (pg/ml) | -0.0603 | 0.6773 | -0.0322 | 0.7129 | -0.0331 | 0.8107 | -0.0425 | 0.5672 |
IL12p70 | Interleukin-12p70 (pg/ml) | -0.1040 | 0.4769 | -0.0482 | 0.5888 | -0.1040 | 0.4632 | -0.0093 | 0.9018 |
Significant p-values (p < 0.001) are denoted with a *.