Table III. Distribution of the Pro and Arg content and HLA-B*07:02 and -B*27:05 ligands in the HRSV proteome.
Long strain proteina | Number of | Number of Pro + Argd | % of Pro + Arge | Number of residuesf | % of proteomeg | Ligandsh | |
---|---|---|---|---|---|---|---|
Prob | Argc | ||||||
L | 68 | 81 | 149 | 46.0 | 2165 | 49.2 | 1 |
F | 16 | 18 | 34 | 10.5 | 573 | 13 | 0 |
G | 26 | 2 | 28 | 8.6 | 186 | 4.2 | 0 |
N | 9 | 16 | 25 | 7.7 | 391 | 8.9 | 4 |
P | 12 | 11 | 23 | 7.1 | 219 | 5 | 1 |
M | 12 | 6 | 18 | 5.6 | 256 | 5.8 | 2 |
M2 | 6 | 11 | 17 | 5.2 | 195 | 4.4 | 1 |
NS2 | 7 | 6 | 13 | 4.0 | 124 | 2.8 | 2 |
M2–2 | 5 | 3 | 8 | 2.5 | 90 | 2 | 0 |
NS1 | 4 | 1 | 5 | 1.5 | 138 | 3.1 | 0 |
SH | 2 | 2 | 4 | 1.2 | 65 | 1.5 | 0 |
a Abbreviations: L (Polymerase), F (Fusion protein), G (Attachment protein), N (Nucleoprotein), P (Phosphoprotein), M (Matrix protein), M2-22k (Matrix protein 22k), NS2 (Non-structural protein 2), M2-2 (Matrix protein 2), NS1 (Non-structural protein 1), and SH (Small hydrophobic protein).
b The number of Pro in the viral proteome.
c The number of Arg in the viral proteome.
d The number of Pro + Arg in the viral proteome.
e The percentage of Pro + Arg included in the viral proteome.
f The total residue number.
g The residue number for each protein/ total residue number, as a percentage.
h The number of HLA-B*07:02 and -B*27:05 ligands in HRSV.