Table 2. EBNA2 peak overlap with immune response gene regions and excess enrichment of case-control analysis.
| ANALYSIS DESCRIPTION | enrichment (O/E) | p-value |
|---|---|---|
| 'EBNA2 peaks' inside 'immune response gene regions' | 3.261 | 0.00012 |
| Preferential overlap of 'EBNA2 peaks' on 'MS regions including MHC' (case) relatively to 'immune response gene regions' (control) | 1.603 1 | 6.00e-05 |
O/E: factor of observed vs expected overlap; 1: enrichment difference (EED).
EBNA2 = Epstein-Barr nuclear antigen 2; RBPJ = Recombination signal-binding protein for immunoglobulin Kappa J region; MHC = Major histocompatibility complex; MS = multiple sclerosis.