Table 2. Estimated limits of detection (LOD), quantification (LOQ), and linearity of LC-MS/MS method for urinary naphthalene metabolite analysis.
Metabolite | LOD (ng/10μl injected) | LOQ (ng/10μl injected) | Linearity | |
---|---|---|---|---|
Range (ng/10μl injected) | Correlation Coefficient (R2) a | |||
Mercapturic Acid | 3.40 | 6.79 | 5–500 | 0.9989 |
N-Acetyl GSH | 1.29 | 2.58 | 1–100 | 0.9930 |
Naphthol Glucuronide | 2.30 | 4.60 | 1–100 | 0.9973 |
Naphthol Sulfate | 0.91 | 1.82 | 1–100 | 0.9940 |
a Average correlation coefficient (n = 5 calibration curves)