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. 2015 Apr 8;10(4):e0123043. doi: 10.1371/journal.pone.0123043

Fig 3. Role of the cGMP signaling pathway in abacavir-induced relaxation of rat basilar arteries.

Fig 3

Rings of rat basilar arteries were treated with ODQ (10 μM) or KT 5823 (1 μM) for 30 min. Rings without inhibitor treatment served as controls. Abacavir-induced relaxation of basilar arteries was then measured. Changes in tension were expressed as the percentage decrease in response to contraction caused by endothelin-1 (ET-1; 1–10 nM). Values are means ± S.E.M of five sets of experiments and statistical comparisons were made using ANOVA. *** P<0.005 compared with control.