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. 2015 Apr 8;10(4):e0123043. doi: 10.1371/journal.pone.0123043

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© 2015 Li et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 8 — Rings of rat basilar arteries were treated with CGS-15943 (1 μM) or ZM-241385 (1 μM) for 30 min. Rings without antagonist treatment served as controls. Abacavir-induced relaxation of rat basilar arteries was then measured. (A) Changes in tension were expressed as a percentage decrease in response to contraction caused by endothelin-1 (ET-1; 1–10 nM). (B) Sample trace showing the effects of CGS-15943 and ZM-241385 on abacavir-induced relaxation. Values are means ± S.E.M of four to five sets of experiments and statistical comparisons were made using ANOVA. ***P <0.005 versus control.