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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Cancer Discov. 2015 Feb 17;5(4):368–379. doi: 10.1158/2159-8290.CD-14-1057

Figure 1. miRSNP association with prostate cancer risk.

Figure 1

Manhattan Plot with −log p-values adjusted for study site and principal components. 2,169 miRSNPs were assessed for association with prostate cancer risk. 22 SNPs representing 16 genes were found to be associated with risk of prostate cancer after correction for multiple testing (p<2.3×10−5). (The 10 most significant SNPs are labelled). KLK3 rs1058205 and VAMP8 rs1010 (in bold) were selected for further functional validation studies. (OR = odds ratio).