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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Cancer Discov. 2015 Feb 17;5(4):368–379. doi: 10.1158/2159-8290.CD-14-1057

Figure 4. miR-3162-5p induces a reduction in KLK3 mRNA and KLK3 protein expression in LNCaP cells homozygous for the rs1058205 T SNP-allele.

Figure 4

(A) qPCR analyses in LNCaP cells revealed a 25% decrease in KLK3 mRNA (p = 0.016) following over-expression of miR-3162-5p compared to the negative control miRNA mimic treatment. (B) Western blot analyses in LNCaP cells revealed a 32% decrease in cellular KLK3 protein (p = 0.007) following over-expression of miR-3162-5p compared to the negative control. (C) Representative Western blot. Mean +/− SD, n = 3. (* = p < 0.05) (** = p < 0.01)