Table 1.
Participant characteristics
| Characteristic | Controls N=22,320 N (%) |
Cases N=22,301 N (%) |
p valuea |
|---|---|---|---|
|
| |||
| Age at diagnosis/interview mean± SD | 60.6±10.7 | 64.8± 8.0 | <.0001 |
|
| |||
| Family history of prostate cancer | <.0001 | ||
| No | 10992(86.1) | 10300(77.9) | |
| Yes | 1779(13.9) | 2918(22.1) | |
|
| |||
| Gleason score | N/A | ||
| 2–6 | 8863(52.6) | ||
| 7 | 5548(32.9) | ||
| 8–10 | 2437(14.5) | ||
|
| |||
| SEER Stage | N/A | ||
| Local | 13246(72.8) | ||
| Distant | 883(4.9) | ||
| Regional | 3555(19.6) | ||
| Unknown | 503(2.8) | ||
|
| |||
| PSA at diagnosis (ng/ml) | N/A | ||
| <100 | 12692(95.7) | ||
| ≥100 | 565(4.3) | ||
|
| |||
| Aggressive diseaseb | N/A | ||
| No | 17504(82.1) | ||
| Yes | 3812(17.9) | ||
|
| |||
| Vital status | <.0001 | ||
| Alive | 4738(72.2) | 13794(85.4) | |
| Prostate-specific death | 0 | 1233(7.6) | |
| Other death | 1822(27.8) | 1134(7.0) | |
a
t-test for a continuous variable and chi-square test for a categorical variable
b
Aggressive disease is defined as a Gleason score of 8–10, PSA at diagnosis≥100 ng/ml, distant stage or prostate cancer-specific death.