Table 2.
Anatomically constrained limbic regions of interest analysis of variance results.
| Group (OB > HW) | Condition (Sucrose > Water) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Region | L/R | Volume (μL) | x | y | z | F | t | g | Volume (μL) | x | y | z | F | t | g |
| Amygdala | L | 184 | −30 | 0 | −16 | 7.2 | 2.8 | 1.1 | -- | -- | -- | -- | -- | -- | -- |
| L | 160 | −20 | −2 | −26 | 6.3 | 2.5 | 1.0 | 208 | −20 | 0 | −18 | 10.0 | 3.2 | 1.3 | |
| L | 144 | −28 | −12 | −14 | 7.6 | 2.8 | 1.1 | -- | -- | -- | -- | -- | -- | -- | |
| R | 1064 | 30 | −2 | −18 | 10.1 | 3.2 | 1.3 | 184 | 20 | 0 | −16 | 8.8 | 3.0 | 1.2 | |
| Insula (anterior) | L | 488 | −38 | 0 | −16 | 8.3 | 2.9 | 1.2 | -- | -- | -- | -- | -- | -- | -- |
| (posterior) | L | 472 | −42 | −12 | 6 | 13.6 | 3.7 | 1.5 | -- | -- | -- | -- | -- | -- | -- |
| (posterior) | R | 1984 | 36 | −4 | −6 | 12.2 | 3.5 | 1.4 | -- | -- | -- | -- | -- | -- | -- |
| Anterior striatum | L | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| R | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | |
Small volume correction was determined with Monte-Carlo simulations (via AFNI’s 3dClustSim) to guard against false positives resulting in an a posteriori ROI-wise probability of p < 0.05; minimum cluster size for amygdala = 112 μL, insula = 178 μL, left anterior striatum = 160 μL, right anterior striatum = 152 μL. Coordinates given in MNI space. L: left; R: right; HW: healthy weight; OB: obese.