Table 3.
Toxicity | AZA alone n=18 |
AZA/belinostat n=14 |
---|---|---|
| ||
Hematologic | ||
Grade 1/2 | 2 | 1 |
Grade 3/4 | 4 | 3 |
| ||
Fatigue | ||
Grade 1/2 | 10 | 9 |
Grade 3/4 | 0 | 0 |
| ||
Injection Site Reaction | ||
Grade 1/2 | 7 | 7 |
Grade 3/4 | 0 | 0 |
| ||
Nausea/Vomiting | ||
Grade 1/2 | 13 | 11 |
Grade 3/4 | 0 | 0 |
| ||
Anorexia | ||
Grade 1/2 | 4 | 3 |
Grade 3/4 | 0 | 0 |
| ||
Diarrhea | ||
Grade 1/2 | 4 | 4 |
Grade 3/4 | 0 | 0 |
| ||
Prolonged QT | ||
Grade 1/2 | 2 | 3 |
Grade 3/4 | 0 | 1 |
| ||
Dizziness | ||
Grade 1/2 | 5 | 1 |
Grade 3/4 | 0 | 0 |
| ||
LFT abnormality | ||
Grade 1/2 | 2 | 0 |
Grade 3/4 | 0 | 1 |
| ||
Hypotension | ||
Grade 1/2 | 4 | 1 |
Grade 3/4 | 0 | 0 |
| ||
Mucositis | ||
Grade 1/2 | 2 | 1 |
Grade 3/4 | 0 | 0 |