Table 6.
Missing At Random (MAR)a
Data Model | Interaction | Statisticsb | Hypothesis Test | Powerc | Type I Errorc |
---|---|---|---|---|---|
Full (CS) | Moderate | ζ t | Last Time Point | 0.193(0.328) | 0.060(0.047) |
ζ ANCOVA | 0.285(0.327) | 0.064(0.044) | |||
ζ FUN | 0.310(0.343) | 0.049(0.049) | |||
ζ MSL | 0.989(0.987) | 0.054(0.046) | |||
ζ MBP | Overall Effect | 0.968(0.965) | 0.054(0.044) | ||
ζ MSA | 0.995(0.995) | 0.054(0.046) | |||
Main Effects (CS) | None | ζ t | Last Time Point | 0.176(0.325) | 0.060(0.047) |
ζ ANCOVA | 0.265(0.331) | 0.064(0.044) | |||
ζ FUN | 0.303(0.338) | 0.049(0.049) | |||
ζ MSL | 0.689(0.710) | 0.054(0.046) | |||
ζ MBP | Overall Effect | 0.463(0.486) | 0.054(0.044) | ||
ζ MSA | 0.689(0.710) | 0.054(0.046) |
results based on 1000 simulations with 100 subjects at each treatment arm
model selection via BIC with 200 bootstrap resampling
values inside parentheses are based on no missing scenario
ζt: t-test for last time point effect
ζANCOVA: test last time point effect via ANCOVA model
ζFUN: test last time point effect via full mixed effect model with UN covariance
ζMSL: model selection test statistics for testing last time point effect
ζMBP: mixed effects model based likelihood ratio test for overall effects
ζMSA: model selection statistics for testing overall effects