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Intracerebroventricular (ICV) administration of vildagliptin in high-salt (HS)-fed Dahl salt-sensitive (DSS) rats. Seven days after HS diet treatment, ICV infusion of vildagliptin (50, 500 and 2500 μg per 10 μl solution) or vehicle (10 μl solution) were performed. Changes in blood pressure (BP; a) and heart rate (HR) (b) were measured for 30 min following the infusion. ICV infusion of vildagliptin does not change either BP or HR.
