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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Cancer Immunol Res. 2015 Jan 27;3(4):389–398. doi: 10.1158/2326-6066.CIR-14-0173

Figure 5. Three-step therapy induces CD4- and CD8-dependent immune responses and requires all therapy components for maximum efficiency.

Figure 5

5A. Mice (7–8/group) were treated and observed similarly to that described for Figure 4 except that different combinations among the three therapy components were used to observe the contribution of each. Tumor areas are mean + SEM. 5B. Mice (9–13/group) were treated and observed as before. Treatments consisted of PBS as control or Dox MP+Ab. Mice receiving three-step therapy additionally received multiple injections of either anti-CD4, anti-CD8, or both according to the schematic shown.