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. Author manuscript; available in PMC: 2015 Apr 9.
Published in final edited form as: Adv Healthc Mater. 2014 Dec 9;4(5):686–694. doi: 10.1002/adhm.201400657

Figure 4.

Figure 4

(a) Tissue culture supernatants from BDC-2.5 splenocytes (5×105) stimulated with 1µM BDC-2.5 mimotope in the presence (+) or absence (−) of 5×106 (PVPON/TA)5 (#1), (PVCL/TA)5 (#2) capsules for 96 hours were assayed for nitrite levels by the Greiss assay. Data shown is representative of 3 independent experiments performed with at least triplicates for each sample . *** p<0.001, ** p<0.005 in comparison to BDC-2.5 mimotope-stimulated samples alone. (b) Schematics of ROS and RNS protection of islets coated by (PVCL/TA) or (PVPON/TA) hydrogen-bonded coatings.