Table 4.

Treatable leukodystrophies.^*.

Disease	Screening test	Treatment
Adrenoleukodystrophy (cerebral)	VLCFA	Bone marrow transplantation in early stages of the disease.
Cerebrotendinous Xanthomatosis	Cholestanol	Chenodeoxycholic acid; inhibitors of HMG-CoA reductase.
Krabbe	Galactocerebrosidase activity assay	Bone marrow transplantation in pre-symptomatic and early symptomatic patients, though the benefit of this is still undergoing testing.
Metachromatic leukodystrophy	Arylsulfatase A activity assay	Bone marrow transplantation in pre-symptomatic and early symptomatic patients though the benefit of this is still undergoing testing.

^*Note, this does not include the many genetic leukoencephalopathies, including but not limited to amino acidemias (MSUD, PKU, etc.), organic acidurias (MMA, IVA, PA, etc.), Niemann-Pick type C, biotinidase deficiency, Wilson's disease, etc.