Inter-male aggression of ephrin-A5−/− and wild-type male mice toward a zinc sulfate treated anosmic intruder was measured in the resident intruder test.
(A) Only two out of ten null mice engaged in aggressive behavior compared to eight out of ten wild-type mice. Data are presented as percent of animals that fought.
(B, C) Ephrin-A5−/− mice had increased latency to the first attack (B) as well as reduced number of attacks (C) compared to wild-type control.
n= 10 per genotype. Data are presented as mean +SEM. * indicates significantly different from wild-type; p<0.001.