Table 2. Second chromosome EP alleles that genetically interact with His1.
EP Allele | EP Males | H1KD + EP: Cy | H1KD + EP: Cy+ | EP: Cy | EP: Cy+ | NE | P (FET) | P (bin) | Gene Symbol | Flybase ID |
---|---|---|---|---|---|---|---|---|---|---|
P{EP}Dap160EP2543 | hom | 135 | 0 | 70 | 4 | 0.00 | 6.1E-08 | 4.3E-10 | Dap160 | FBgn0023388 |
P{EP}G3075 | hom | 92 | 0 | 58 | 5 | 0.00 | 1.2E-07 | 3.0E-13 | bsh | FBgn0000529 |
P{EP}G18270 | hom | 135 | 0 | 97 | 6 | 0.00 | 6.1E-06 | 4.3E-08 | phyl | FBgn0013725 |
P{EP}gbbG12649 | het | 66 | 0 | 31 | 24 | 0.00 | 1.2E-07 | 4.1E-11 | gbb | FBgn0024234 |
P{EP}G2573 | hom | 67 | 0 | 87 | 3 | 0.00 | 2.6E-06 | 2.8E-11 | CG10631 | FBgn0032817 |
P{EP}G3720 | hom | 63 | 0 | 114 | 36 | 0.00 | 6.4E-06 | 1.3E-10 | CG15611 | FBgn0034194 |
P{EP}slimG8310 | hom | 81 | 0 | 56 | 8 | 0.00 | 5.8E-07 | 1.7E-09 | slim | FBgn0261477 |
P{EP}mrjEU639 | hom | 111 | 0 | 107 | 2 | 0.00 | 2.8E-03 | 8.6E-03 | mrj | FBgn0034091 |
P{EP}painEP2251 | hom | 113 | 0 | 81 | 2 | 0.00 | 1.3E-04 | 2.2E-04 | pain | FBgn0060296 |
P{EP}RpS15G3660 | het | 73 | 1 | 141 | 55 | 0.11 | 1.9E-06 | 1.0E-09 | RpS15 | FBgn0034138 |
P{EP}CG5846G2283 | hom | 63 | 2 | 71 | 76 | 0.16 | 2.5E-05 | 3.8E-08 | CG5846 | FBgn0032171 |
P{EP}visG2720 | hom | 65 | 3 | 39 | 39 | 0.23 | 7.8E-04 | 1.0E-07 | vis | FBgn0033748 |
P{EP}MESK2EP2347 | hom | 62 | 4 | 18 | 35 | 0.24 | 4.1E-03 | 1.5E-06 | MESK2 | FBgn0043070 |
P{EP}CG5742G8286 | hom | 97 | 3 | 68 | 31 | 0.25 | 2.0E-05 | 3.5E-12 | CG5742 | FBgn0034304 |
P{EP}G2957 | hom | 82 | 4 | 56 | 42 | 0.28 | 7.1E-03 | 4.2E-05 | hbs | FBgn0029082 |
P{EP}Nedd8G7338 | hom | 87 | 5 | 99 | 97 | 0.29 | 2.6E-07 | 3.3E-13 | Nedd8 | FBgn0032725 |
P{EP}TBCBG2655 | het | 82 | 4 | 35 | 19 | 0.30 | 3.5E-03 | 1.0E-03 | TBCB | FBgn0034451 |
P{EP}CG13751G18007 | hom | 72 | 4 | 82 | 62 | 0.32 | 1.1E-03 | 6.6E-08 | CG13751 | FBgn0033340 |
P{EP}CG8155G2736 | hom | 105 | 6 | 92 | 71 | 0.32 | 2.0E-04 | 7.2E-11 | CG8155 | FBgn0034009 |
P{EP}CG3838G18268 | hom | 57 | 6 | 33 | 44 | 0.41 | 3.3E-03 | 9.8E-05 | CG3838 | FBgn0032130 |
P{EP}Ipk2G3545 | hom | 135 | 12 | 141 | 135 | 0.41 | 2.9E-07 | 1.7E-14 | Ipk2 | FBgn0031267 |
P{EP}nopoG5845 | hom | 59 | 6 | 48 | 50 | 0.44 | 3.3E-03 | 6.7E-05 | nopo | FBgn0034314 |
P{EP}invGE10665 | hom | 76 | 1 | 49 | 4 | 0.46 | 7.7E-06 | 2.6E-11 | inv | FBgn0001269 |
P{EP}leaEP2582 | hom | 54 | 1 | 106 | 12 | 0.47 | 2.5E-04 | 7.1E-08 | lea | FBgn0002543 |
P{EP}zf30CG2920 | hom | 64 | 1 | 68 | 6 | 0.50 | 4.8E-05 | 2.3E-09 | zf30C | FBgn0022720 |
P{EP}EP437 | hom | 71 | 6 | 65 | 39 | 0.51 | 6.7E-03 | 2.6E-06 | GEFmeso | FBgn0050115 |
P{EP}coroGE15547 | hom | 84 | 13 | 45 | 64 | 0.52 | 9.2E-03 | 1.0E-04 | coro | FBgn0265935 |
P{EP}spictEP2202 | hom | 94 | 19 | 37 | 79 | 0.54 | 9.4E-03 | 1.0E-03 | spict | FBgn0032451 |
P{EP}CG12484EP2424 | hom | 99 | 12 | 77 | 61 | 0.57 | 2.4E-04 | 8.0E-15 | CG12484 | FBgn0086604 |
P{EP}AGO1G2846 | hom | 81 | 10 | 67 | 52 | 0.59 | 3.2E-03 | 1.8E-05 | AGO1 | FBgn0262739 |
P{EP}Pka-R2EP2162 | hom | 117 | 18 | 72 | 73 | 0.60 | 5.3E-03 | 3.7E-06 | Pka-R2 | FBgn0022382 |
P{EP}CG3358G7969 | hom | 71 | 14 | 35 | 49 | 0.62 | 9.3E-03 | 4.4E-03 | CG3358 | FBgn0033117 |
P{EP}CG3476G2643 | hom | 103 | 17 | 76 | 77 | 0.63 | 4.0E-03 | 1.3E-10 | CG3476 | FBgn0031881 |
P{EP}spiEP2378 | het | 90 | 10 | 137 | 59 | 0.63 | 7.9E-04 | 1.4E-11 | spi | FBgn0005672 |
P{EP}RtGEFG3647 | hom | 51 | 9 | 95 | 105 | 0.63 | 5.3E-03 | 3.2E-06 | RtGEF | FBgn0015803 |
P{EP}uzipEP1153 | hom | 113 | 21 | 67 | 73 | 0.66 | 8.5E-03 | 1.9E-08 | uzip | FBgn0004055 |
P{EP}Arf51FEP2612 | hom | 136 | 22 | 110 | 91 | 0.68 | 1.5E-03 | 3.2E-13 | Arf51F | FBgn0013750 |
P{EP}homerEP2141 | hom | 104 | 18 | 67 | 59 | 0.69 | 9.5E-03 | 8.8E-09 | homer | FBgn0025777 |
P{EP}Oatp30BEP2644 | hom | 94 | 16 | 91 | 77 | 0.70 | 7.8E-03 | 3.9E-08 | Oatp30B | FBgn0032123 |
P{EP}G19340 | hom | 128 | 24 | 110 | 96 | 0.73 | 7.5E-03 | 9.9E-08 | Gbp | FBgn0034199 |
P{EP}G3678 | hom | 124 | 23 | 114 | 85 | 0.79 | 9.7E-03 | 2.6E-07 | CG13220 | FBgn0033608 |
P{EP}CG12744GE13306 | hom | 65 | 43 | 30 | 29 | 1.27 | 9.6E-03 | 4.7E-03 | CG12744 | FBgn0033459 |
P{EP}stauG2796 | hom | 101 | 65 | 69 | 70 | 1.28 | 2.2E-03 | 1.4E-03 | stau | FBgn0003520 |
P{EP}lolaEP2537 | het | 91 | 38 | 106 | 51 | 1.28 | 8.5E-03 | 6.3E-03 | lola | FBgn0005630 |
P{EP}G2086 | hom | 69 | 48 | 60 | 59 | 1.28 | 8.1E-03 | 2.1E-03 | Spp | FBgn0031260 |
P{EP}Sep5G6155 | hom | 50 | 55 | 42 | 98 | 1.31 | 3.8E-06 | 1.2E-07 | Sep5 | FBgn0026361 |
P{EP}EP2520 | het | 116 | 59 | 97 | 46 | 1.34 | 2.4E-03 | 2.4E-03 | Lar | FBgn0000464 |
P{EP}E(Pc)EP608 | hom | 86 | 55 | 99 | 109 | 1.34 | 2.5E-03 | 1.4E-03 | E(Pc) | FBgn0000581 |
P{EP}ThiolaseG3215 | hom | 69 | 56 | 56 | 55 | 1.35 | 1.1E-03 | 9.1E-04 | Thiolase | FBgn0025352 |
P{EP}EDTPEP2390 | hom | 68 | 69 | 78 | 84 | 1.37 | 1.4E-03 | 2.2E-04 | EDTP | FBgn0027506 |
P{EP}G12586 | hom | 82 | 67 | 82 | 94 | 1.39 | 7.9E-03 | 6.7E-03 | CG13551 | FBgn0040660 |
P{EP}CG43340G19466 | hom | 71 | 63 | 92 | 88 | 1.40 | 2.9E-04 | 7.3E-05 | CG43340 | FBgn0263077 |
P{EP}Elba2G17999 | hom | 54 | 44 | 88 | 76 | 1.43 | 2.3E-03 | 2.0E-03 | Elba2 | FBgn0031435 |
P{EP}Socs36EG2762 | hom | 93 | 76 | 70 | 58 | 1.47 | 5.3E-04 | 1.1E-04 | Socs36E | FBgn0041184 |
P{EP}EP993 | hom | 51 | 44 | 68 | 57 | 1.48 | 1.3E-03 | 1.1E-03 | CG30069 | FBgn0050069 |
P{EP}EP2515 | het | 67 | 44 | 98 | 39 | 1.59 | 5.8E-03 | 3.2E-03 | dnr1 | FBgn0260866 |
P{EP}pAbpEP310 | hom | 78 | 41 | 106 | 57 | 1.62 | 5.5E-03 | 2.7E-03 | pAbp | FBgn0265297 |
P{EP}JhI-21GE15185 | hom | 113 | 35 | 106 | 36 | 1.74 | 7.2E-03 | 4.9E-06 | Jhl-21 | FBgn0028425 |
P{EP}G2213 | hom | 61 | 35 | 173 | 54 | 1.97 | 7.4E-03 | 3.8E-03 | Chd1 | FBgn0250786 |
P{EP}c(2)MEP2115 | hom | 43 | 52 | 42 | 21 | 2.15 | 1.3E-05 | 1.7E-06 | c(2)M | FBgn0028525 |
P{EP}Traf4EP578 | hom | 84 | 5 | 91 | 0 | INF | 7.1E-04 | 1.1E-08 | Traf4 | FBgn0026319 |
Statistically significant results of the viability-based screen for genetic modifiers of His1 are presented. EP Allele, the second chromosome EP insertion allele identifier; EP Males, the homozygous/heterozygous males used in the screen and control crosses; H1KD + EP: Cy, the number of balancer-carrying adult F1 progeny in the screen cross; H1KD + EP: Cy+, the number of Act5C-GAL4, pINT-H14M/P{EP} adult F1 progeny; EP: Cy, the number of balancer-carrying adult F1 progeny in the control cross; EP: Cy+, the number of Act5C-GAL4/P{EP} adult F1 progeny; NE, normalized effect of the EP allele on H1KD adult viability; P (FET), probability value from the Fisher’s exact test; P (bin), probability value from the binomial test. A gene symbol (conventional gene name) and its associated Flybase ID are shown for genes that are affected by every particular EP allele.