TABLE 1.

Clinical manifestations and outcomes for patients infected with MSSA or S. argenteus

Clinical parameter	Data for patients witha:		P valueb
	MSSA	S. argenteus
Total cases	199	10
Age (yr)	38 (14–59, 1–84)	56.5 (41–66, 11–73)	0.04
Sex (male)	118 (59)	7 (70)	0.74
Blood culture-positive isolates	56 (28)	3 (30)	>0.99
Place of acquisition
Community acquired	172 (86)	8 (80)	0.63
Health care associatedc	27 (14)	2 (20)
Underlying medical conditiond	65 (33)	7 (70)	0.03
Cardiac diseasee	12 (6)	1 (10)	0.48
Diabetes mellitus	29 (15)	6 (60)	0.002
Renal diseasef	15 (8)	6 (60)	<0.001
Immunosuppressiong	25 (13)	2 (20)	0.62
Lung diseaseh	9 (5)	1 (10)	0.39
Pattern of disease
Identified site, bacteremia only	17 (9)	2 (20)	0.19
1 identified site	155 (78)	6 (60)
>1 identified site	27 (13)	2 (20)
Other identifiable sites of infection
Superficial abscess	81 (41)	4 (40)	0.15
Deep abscess	45 (23)	0
Other skin and soft tissue infections	21 (11)	4 (40)
Bone and joint infections	24 (12)	2 (20)
Prosthetic material infection	13 (7)	0
Respiratory infection	14 (7)	0
Endocarditis	6 (3)	0
Other infection	7 (4)	0
Outcome
Cured	150 (75)	7 (70)	0.58
Treatment failure	11 (6)	1 (10)
Death due to S. aureus	26 (13)	1 (10)
Death due to other causes	12 (6)	1 (10)

^aData shown are number (%) or median (interquartile range, range).

^bP values were estimated using Fisher's exact test. Values for age were estimated using the Mann-Whitney test.

^cHealth care-associated infections included nosocomial and nonnosocomial health care-associated infections (12).

^dPast medical history of any underlying chronic medical conditions reported by the patients and/or relatives or recorded in the medical notes.

^e“Cardiac disease” comprised congenital heart disease, valvular heart disease (including rheumatic heart disease), ischemic disease, or arrhythmias (including heart block requiring pacemaker).

^f“Renal disease” included end-stage renal failure with long-term dialysis and chronic renal failure (not on dialysis) due to diabetes mellitus, systematic lupus erythematous, multiple myeloma, glomerulonephritis, or an unknown etiology.

^gImmunosuppression included that from HIV, chemotherapy, untreated leukemia, radiotherapy, or immunosuppressive medications, including >30 mg/day of prednisolone for >1 week.

^h“Lung disease” comprised previously treated tuberculosis, previous empyema, lung cancer, long-term tracheostomy, chronic obstructive pulmonary disease, or asthma.