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. 2015 Feb 19;53(3):1002–1004. doi: 10.1128/JCM.03609-14

TABLE 1.

Performance of pooled processed DNA compared to that of individually tested samples

Bacterium No. of pools tested Total no. (%) of presumptive positives in the pool No. of positive pools with positive individual results (% true positives) No. of positive pools with negative individual results (% false positives) No. of negative pools with negative individual results (% true negatives) No. of negative pools with positive individual results (% false negatives) Specificity of pool (%) Sensitivity of pool (%) PPVa (%) NPVb (%)
S. pneumoniae 119 82 (69) 78 (65) 4 (3) 33 (28) 4 (3) 89 95 95 89
H. influenzae 119 63 (53) 60 (50) 3 (2) 55 (46) 1 (1) 95 98 95 98
K. pneumoniae 119 63 (53) 46 (39) 17 (14) 54 (45) 2 (2) 76 96 73 96
Total 357 208 (58) 184 (52) 24 (7) 142 (40) 7 (2) 86 96 88 95
a

PPV, positive predictive value.

b

NPV, negative predictive value.