TABLE 2.
Pathogen | Pathogen yield result for: |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
ABXc,d present (n = 12,091) |
ABXc,d not present (n = 34,575) |
|||||||||||
F bottle |
MB bottle |
Difference in yield (MB − F) |
F bottle |
MB bottle |
Difference in yield (MB − F) |
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No. | % | No. | % | % | McNemar's P | No. | % | No. | % | % | McNemar's P | |
Burkholderia pseudomalleie | 98 | 0.81 | 178 | 1.47 | 0.66 | <0.0001 | 295 | 0.85 | 311 | 0.90 | 0.05 | 0.1131 |
Escherichia coli | 168 | 1.39 | 163 | 1.35 | −0.04 | 0.5737 | 1,128 | 3.26 | 1,050 | 3.04 | −0.22 | 0.0002 |
Klebsiella pneumoniae | 59 | 0.49 | 52 | 0.43 | −0.06 | 0.0896 | 363 | 1.05 | 332 | 0.96 | −0.09 | 0.0068 |
Salmonella speciesf | 25 | 0.21 | 19 | 0.16 | −0.05 | 0.0143 | 179 | 0.52 | 158 | 0.46 | −0.06 | 0.0127 |
Staphylococcus aureus | 31 | 0.26 | 20 | 0.17 | −0.09 | 0.0076 | 261 | 0.75 | 245 | 0.71 | −0.04 | 0.0455 |
Streptococcus pneumoniae | 4 | 0.03 | 4 | 0.03 | 0.00 | 1.0000 | 110 | 0.32 | 75 | 0.22 | −0.10 | <0.0001 |
Streptococcus pyogenes | 5 | 0.04 | 1 | 0.01 | −0.03 | 0.1025 | 102 | 0.30 | 78 | 0.23 | −0.07 | 0.0001 |
Total pathogens | 390 | 3.2 | 437 | 3.6 | 0.04 | 0.0022 | 2,438 | 7.1 | 2,249 | 6.5 | 0.6 | <0.0001 |
Selected subset of commonly identified pathogens.
BacT/Alert FA (PF for children <5 years old) and BacT/Alert MB (F and MB) bottles were used.
ABX, antimicrobial activity.
ABX presence was determined by antimicrobial activity in patient sera at the time of blood collection (4).
Numbers in this table are lower than those in Table 1, because antibiotic activity data were not available for all cases.
All nontyphoidal Salmonella species.