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. 2015 Apr 1;35(3):314–320. doi: 10.3343/alm.2015.35.3.314

Table 2. Laboratory and clinical characteristics of five renal allograft rejection patients with anti-AT1R-positive results.

Pt Pt, Sex/age pre-transplant At the time of biopsy
No. of HLA MM CDC (T/B) FCXM (T/B) HLA Abs DSA desensitization HTN Anti-AT1R (U/mL) HLA Abs DSA de-novo DSA graft failure ARB Histological diagnosis C4d
1 M/25 2 N/N N/N N N N P 11.5 N N N N N Acute TCMR, type IA N
2 M/25 6 N/N P/P NA NA P N 10.1 P P NA N N Chronic active AMR, type II P
3 M/40 2 N/N N/N N N N P 17.5 P P P P P Chronic active AMR P
4 F/53 2 P/N P/P P P P N 10.3 P P N N N C4d-negative AMR, type II N
5 F/43 6 N/N N/N N N N N 11.2 P P P N N Acute TCMR, type IIA P
Acute AMR, type II

Abbreviations: N, negative; P, positive; NA, not available; M, male; F, female; Pt, patients; CDC, complement dependent cytotoxicity crossmatch; FCXM, flow cytometry crossmatch; Abs, antibodies; HTN, hypertension; ARB, angiotensin II receptor blocker; DSA, donor specific HLA antibodies; AMR, antibody-mediated rejection; TCMR, T-cell-mediated rejection; MM, mismatch; T/B, T cell/B cell.