Table 2. Meta-analysis results of all studies and each subgroup studies.
Cases | Heterogeneity analysis | Pooled SMD | 95% CI | ||
---|---|---|---|---|---|
I2 (%) | P value | ||||
Variant genotype* | 526 | 31 | 0.12 | 0.03 | -0.07-0.13 |
China populations† | 158 | 49 | 0.07 | 0.03 | -0.15-0.21 |
Variant genotype (T/C)‡ | 284 | 63 | 0.02 | 0.06 | -0.08-0.20 |
Variant genotype (C/C)§ | 22 | 0 | 0.41 | -0.15 | -0.57-0.28 |
Variant genotype (T/C & C/C)∥ | 220 | 0 | 0.55 | 0.01 | -0.15-0.16 |
*Analysis of the association between the lipid-lowering efficacy of statins and SLCO1B1 c.521T>C polymorphism; †Analysis of the association between the lipid-lowering efficacy of statins and SLCO1B1 c.521T>C polymorphism in Chinese populations; ‡Analysis of the association between the lipid-lowering efficacy of statins and SLCO1B1 variant heterozygotes (T/C); §Analysis of the association between the lipid-lowering efficacy of statins and SLCO1B1 variant homozygotes (C/C); ∥These studies did not provide the cases of single heterozygote (T/C) or homozygote (C/C).
Abbreviations: SMD, standard mean difference; CI, confidence interval.