Fig. 2. Chromosome and microarray analyses. Giemsa-banded karyogram of the bone marrow cells at diagnosis: 46,XY,i(17)(q10). The arrow denotes the abnormal chromosome (A). Microarray analysis shows a single copy loss in chromosome 17 at bands p13.3 through p11.2, and a single copy gain of chromosome 17 at bands p11.2 through q25.3 [arr 17p13.3p11.2(64,214-18,751,820)×1, 17p11.2q25.3(18,751,820-80,587,411)×3] (B). SNP array analysis shows homozygosity in the long arm of chromosome 7, at band q11.1, which is approximately 135.9 megabases [arr 7q11.1q36(59,000,001-159,138,663)×2 homozygous (hmz)] (Affymetrix cytogenetics 2.7M array; Affymetrix, Santa Clara, CA, USA) (C).
