Table 1.
Neural genes altered ≥2.5 fold in the cerebellum of male pups from mothers having FA supplementation during gestation at 20 mg/kg in comparison to mothers at 2 mg/kg diet.
| Accession | Symbol | Fold Change | Direction of Change | Pathway |
|---|---|---|---|---|
| ref|NM_146087 | Csnk1a1 | −3.90 | ↓ | Circadian |
| ref|NM_007771 | Cry1 | −2.70 | ↓ | Circadian |
| ref|NM_172523 | Slc18a2 | −3.81 | ↓ | Dopa-Serotonin |
| ref|NM_201607 | Pde4c | −3.11 | ↓ | Dopa-Serotonin |
| ref|NM_010484 | Slc6a4 | −3.06 | ↓ | Dopa-Serotonin |
| ref|NM_008740 | Nsf | −3.40 | ↓ | GABA-glutamate |
| ref|NM_001130444 | Hras1 | −4.63 | ↓ | Gap-Junctions |
| ref|NM_009446 | Tuba3a | −3.17 | ↓ | Gap-Junctions |
| ref|NM_023279 | Tubb3 | −2.76 | ↓ | Gap-Junctions |
| ref|NM_023716 | Tubb2b | −2.71 | ↓ | Gap-Junctions |
| ref|NM_007659 | Cdk1 | −2.53 | ↓ | Gap-Junctions |
| ref|NM_008235 | Hes1 | −3.17 | ↓ | Neurogenesis |
| ref|NM_001039104 | Trpm1 | −3.36 | ↓ | Neuronal-Ion channel |
| ens|ENSMUST00000105918 | Kcnq1 | −3.29 | ↓ | Neuronal-Ion channel |
| ref|NM_144939 | Frs3 | −6.24 | ↓ | Neurotrophin-receptor |
| ref|NM_053075 | Rheb | −3.13 | ↓ | Synaptic Plasticity |
| ref|NM_138305 | Adcy3 | 2.71 | ↑ | Dopa-Serotonin |
| ref|NM_019840 | Pde4b | 2.57 | ↑ | Dopa-Serotonin |
| ref|NM_009007 | Rac1 | 2.73 | ↑ | Neurogenesis |
| ref|NM_011913 | Best1 | 2.62 | ↑ | Neuronal-Ion channel |
| ref|NM_009314 | Tacr2 | 2.73 | ↑ | Neurotransmitter |
| ref|NM_009750 | Ngfrap1 | 2.92 | ↑ | Neurotrophin-receptor |
↓ = Down regulated; ↑ = Up regulated.